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Forms of Vaccine Support Designs

To stop the effects or spread of a disease through a vaccine a proper vaccine has to be in place for the specific disease that should have particular characteristics relating to the relevant disease. For a vaccine to meet its purpose in the right manner of functionality it should working such a manner that it fights the microbes that cause the disease without affecting or altering other elements of the body functionality. A good vaccine is one that is used in the right manner by the immune system body cells without affecting the infected cells in the body or altering their functionality. Additionally there are some factors that should be considered when coming up with an effective vaccine which should be how friendly the medicine is with other forms of treatment and the region the patients are in the world just to mention a few of the considerations.

The main type of support vaccines are five and will be discussed in the article and they are: toxic vaccine, inactive vaccine, attenuate vaccine, subunit vaccine and conjugate vaccine. Live, attenuated vaccine is a type of vaccine that is developed in the laboratory where the real microbe is weakened to a level that is not harmful to the body. By developing a microbe in the lab it is to create a similar environment of that which the virus or bacteria thrives on so as to learn how it actually behaves in the body. For the purpose of gaining more insight on how to develop a more effective medicine to fight the microbe in the various diseases with the first aim to targeting on knowing the amount of antibodies the body can produce to protect itself from a microbe and designing drugs that would heal one after taking a few doses. Some example of such vaccine support diseases are smallpox vaccine, yellow fever, measles, mumps, rubella, chickenpox and rotavirus.

The other form of support vaccines is the toxic vaccine caused by bacteria that produce harmful chemicals. The bacteria toxin becomes the main cause of illness. It has been learnt from scientific findings that inactive toxins can be treated with formalin, a solution of formaldehyde and sterilized water as vaccine. After the body is immunized it learns how to fight the natural toxic substance by releasing antibodies that fight the toxic substance and finally stop its production. Diphtheria and tetanus are some of the common produced toxic substance by the body.

Thirdly, when designing a conjugate vaccine the scientists link toxoids or antigens from a microbe to the immune system to recognize it to the polysaccharides where this linkage helps immature immune system like that of an infant to react to polysaccharide coating and defend that body against diseases caused by bacterium. A sugar molecules coat a bacterium that disguises the bacterium antigens for the immune system of an infant not to react to them is referred to as polysaccharides.

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